Preop Lactate

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Preop Lactate

Description

Most recent preoperative arterial lactate within 365 day

References:

1.Frank H. Wians, Jr., PhD; Merck Manuel, professional version; Blood Tests: Normal Values; accessed 10-17-2016; http://www.merckmanuals.com/professional/appendixes/normal-laboratory-values/blood-tests-normal-values#v8508814

2. Farmacotherapeutisch kompass, 2016, the Netherlands; published 10-01-2016; accessed 10-17-2016; https://www.farmacotherapeutischkompas.nl/bladeren-volgens-boek/inleidingen/inl-referentiewaarden-klinische-chemie

3. FDA, investigations operations manual 2015, appendix C, Blood Serum Chesitry – Normal Values ; published 2015, accessed 10-17-2016; http://www.fda.gov/downloads/ICECI/Inspections/IOM/UCM135835.pdf

4. Oster Y, Wexler ID, Heyman SN, Fried E.; Recoverable, Record-High Lactic Acidosis in a Patient with Glycogen Storage Disease Type 1: A Mixed Type A and Type B Lactate Disorder.Case Rep Med. 2016;2016:4362743.

Limitation

This collation does not set “normal” ranges for the values. Valid ranges account only for data collection extremes.

Data quality is limited to individual site documentation accuracy, completeness, and variable mapping, which is performed by each site, independently. MPOG, as the coordinating center, reviews data quality at each data upload and monthly via Data Diagnostics and Case Validation tools. This review, while thorough, may not contain all data elements relevant to this phenotype and thus should be carefully reviewed by the user.

Value Type

Numeric

Enumeration

Value	Value Code	Definition

Return Columns

Name	Data Type

Granularity

Logic

Step 1. Collect all of the lactate values brought in from the concepts below.

Concept ID	Concept Name
3410	POC - Blood gas - Lactate (unknown sample type) (mmol/L)
3479	POC - Blood gas - Lactate (unknown sample type) (mg/dL)
5018	Formal lab - Lactate, Serum/Plasma (mmol/L)
3483	Formal lab - Lactate, Serum/Plasma (mg/dL)
5040	Formal lab - Blood gas - Lactate (unknown sample type) (mmol/L)
3484	Formal lab - Blood gas - Lactate (unknown sample type) (mg/dL)
5086	Formal lab - Blood gas - Lactate (arterial) (mmol/L)
3494	Formal lab - Blood gas - Lactate (arterial) (mg/dL)

Step 2. For values brought in by concepts reported in mg/dL convert to mmol/L.

mg/dL ---> multiply by 9.01 to convert to mmol/L

Step 3. Obtain most recent (latest) valid arterial lactate prior to anesthesia start and within 365 days of anesthesia start with number of days prior to surgery

Valid >0 mmol/L and <30 mmol/L
If data invalid ? Output = -998
If data valid ? Output = (numeric value)
If multiple values for the same time, return the highest.

General reference ranges

0.5-2.2 mmol/l (SI unit) 1,2,3
Extreme: 27 mmol/l 4
All values reported in mmol/L